KRTAP13-1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KRTAP13-1 mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP13-1-associated genes across cancer lineages are MEK1, Notch1, and Rab11. Each is linked with KRTAP13-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP13-1-to-partner and partner-to-KRTAP13-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP13-1→partner) and Y-score (partner→KRTAP13-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMEK1 →+0.553+3.459.002.00532
UCECNotch1 →+0.183+2.321.009.03532
UCECRab11 →-0.150-2.321.040.03532
UCECShc_pY317 →-0.213-2.321.005.03532
UCECCD49b →-0.332-2.980.020.03632
UCECDi-Ras3 →-0.197-3.459.008.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Exploration