Across TCGA patient cohorts, KRTAP12-3 mutation is significantly associated with the RNA expression of many other genes, with 83 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP12-3-associated genes across cancer lineages are MIR4497, MIR3909, and RNU6-737P. Each is linked with KRTAP12-3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP12-3-to-partner and partner-to-KRTAP12-3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP12-3→partner) and Y-score (partner→KRTAP12-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR4497 →	+0.558	+2.941	<.001	.001	3	2
UCEC	MIR3909 →	+0.476	+3.156	.001	.006	3	2
SKCM	RNU6-737P →	+0.294	+3.748	<.001	.002	3	2
SKCM	VPS26AP1 →	+0.052	+2.784	<.001	.003	3	1
SKCM	RN7SL288P →	+0.080	+3.181	<.001	.002	3	1
SKCM	RN7SL869P →	+0.068	+4.810	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 83 associations by consensus.

Exploration

KRTAP12-3 survival (RNA) · tumor vs normal (RNA) · all KRTAP12-3 data types