Across TCGA patient cohorts, KRTAP10-8 mutation is significantly associated with the RNA expression of many other genes, with 1,278 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible KRTAP10-8-associated genes across cancer lineages are OR10P1, RNU6ATAC22P, and DEFB121. Each is linked with KRTAP10-8 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRTAP10-8-to-partner and partner-to-KRTAP10-8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP10-8→partner) and Y-score (partner→KRTAP10-8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OR10P1 →	+0.201	+2.512	.007	.007	3	3
UCEC	RNU6ATAC22P →	+0.511	+3.260	<.001	.002	3	3
LUAD	DEFB121 →	+0.058	+4.122	<.001	.009	3	3
LUAD	UQCRBP2 →	+0.437	+4.093	<.001	.001	3	3
LUAD	YWHAQP1 →	+0.156	+3.584	<.001	.002	3	3
BRCA	NF1P7 →	+0.085	+5.760	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,278 associations by consensus.

Exploration

KRTAP10-8 survival (RNA) · tumor vs normal (RNA) · all KRTAP10-8 data types