KRTAP10-8

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KRTAP10-8 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP10-8-associated genes across cancer lineages are Fibroblasts, Th2 cells, and Macrophages M2. Each is linked with KRTAP10-8 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP10-8-to-partner and partner-to-KRTAP10-8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP10-8→partner) and Y-score (partner→KRTAP10-8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIRPFibroblasts →+0.030+5.301.001.04832
UCECTh2 cells →+0.209+3.169.034.02031
SKCMMacrophages M2 →-0.022-2.952.021.03621
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

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