Across TCGA cell cohorts, KRTAP10-8 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KRTAP10-8-associated genes across cancer lineages are H2BC1, H2AC1, and KRTAP10-1. Each is linked with KRTAP10-8 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP10-8-to-partner and partner-to-KRTAP10-8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP10-8→partner) and Y-score (partner→KRTAP10-8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	H2BC1 →	+0.433	+5.977	<.001	.001	3	1
SOFT_TISSUE	H2AC1 →	+0.193	+5.977	<.001	.001	3	1
SOFT_TISSUE	KRTAP10-1 →	+0.034	+5.369	.002	.004	3	1
SOFT_TISSUE	GAGE12E →	+0.090	+4.930	<.001	.008	3	1
BLOOD_Leukemia	TGM7 →	+0.113	+4.037	.001	.004	3	1
BLOOD_Leukemia	BEND2 →	+0.013	+3.551	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

KRTAP10-8 survival (RNA) · tumor vs normal (RNA) · all KRTAP10-8 data types