KRTAP10-5

Across TCGA patient cohorts, KRTAP10-5 mutation is significantly associated with the RNA expression of many other genes, with 174 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible KRTAP10-5-associated genes across cancer lineages are MIR513A2, CIR1P3, and RNU7-196P. Each is linked with KRTAP10-5 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP10-5-to-partner and partner-to-KRTAP10-5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR513A2 grouped by KRTAP10-5-low versus KRTAP10-5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP10-5→partner) and Y-score (partner→KRTAP10-5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR513A2 →	+0.184	+4.049	<.001	.008	3	2
SKCM	CIR1P3 →	+0.049	+3.186	<.001	.006	3	2
BRCA	RNU7-196P →	+0.453	+4.739	<.001	.005	3	2
HNSC	MIR5591 →	+0.698	+7.954	<.001	.008	3	2
BRCA	RNU6-1150P →	+0.285	+3.812	.007	.007	3	2
BRCA	LINC02563 →	+0.163	+4.857	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 174 associations by consensus.

MIR513A2 by KRTAP10-5 expression — UCEC

Explore this box plot interactively →