KRTAP10-5

Across TCGA pan-cancer cohorts, KRTAP10-5 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated KRTAP10-5 data layer compared with 2 for mutation status.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher KRTAP10-5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KRTAP10-5 expression acts as an unfavorable survival marker, although some lineages such as SCLC show a favorable association.

KIRP, LUAD, and HNSC are the cancer types where KRTAP10-5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	II,III,IV	0.127	0.859	<.001	117	view →
LUAD	DFS	Tertile	IV	0.342	0.893	<.001	63	view →
HNSC	OS	Tertile	All	0.238	0.612	.002	45	view →
SCLC	OS	Tertile	All	0.806	0.589	.018	30	view →
ESCA	OS	Tertile	All	0.269	0.548	.023	27	view →
UCEC	DFS	Tertile	All	0.806	0.903	.017	18	view →
BRCA	DFS	Tertile	All	0.371	0.532	.014	12	view →
GBM	DFS	Tertile	All	0.093	0.245	.040	9	view →
SKCM	OS	Tertile	All	0.215	0.343	.036	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

KRTAP10-5–KIRP (OS)

Open the KIRP breakdown →