Across TCGA patient cohorts, KRTAP10-4 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP10-4-associated genes across cancer lineages are Notch1, PDCD4, and Fibronectin. Each is linked with KRTAP10-4 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRTAP10-4-to-partner and partner-to-KRTAP10-4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP10-4→partner) and Y-score (partner→KRTAP10-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.219	+3.013	.001	.018	3	3
UCEC	PDCD4 →	-0.620	-2.459	.006	.020	3	2
UCEC	Fibronectin →	-0.325	-3.160	.041	.019	3	1
UCEC	INPP4B →	-0.367	-2.446	.018	.020	3	1
UCEC	Ku80 →	+0.258	+3.598	.024	.001	3	1
UCEC	mTOR_pS2448 →	-0.192	-3.150	.007	.019	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

KRTAP10-4 survival (RNA) · tumor vs normal (RNA) · all KRTAP10-4 data types