Across TCGA pan-cancer cohorts, KRTAP10-3 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated KRTAP10-3 data layer compared with 14 for mass-spec protein.
The strongest signal is observed in colon adenocarcinoma (COAD), where higher KRTAP10-3 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KRTAP10-3 expression acts as an unfavorable survival marker.
COAD, SARC, and LUAD are the cancer types where KRTAP10-3 Mutation most reproducibly stratifies survival.
Mutation survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.