KRTAP10-3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KRTAP10-3 mutation is significantly associated with the RNA expression of many other genes, with 120 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP10-3-associated genes across cancer lineages are RNU7-14P, OR7E53P, and SNRPGP7. Each is linked with KRTAP10-3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP10-3-to-partner and partner-to-KRTAP10-3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP10-3→partner) and Y-score (partner→KRTAP10-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU7-14P →+1.036+4.437<.001.00132
UCECOR7E53P →+0.063+3.344.007.00832
UCECSNRPGP7 →+0.430+4.920<.001<.00132
UCECPPIAP71 →+0.405+3.585<.001.00932
LUADNF1P10 →+0.319+5.554<.001.00432
LUADNF1P11 →+0.193+5.410<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 120 associations by consensus.

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