Across TCGA patient cohorts, KRTAP10-10 mutation is significantly associated with the RNA expression of many other genes, with 420 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP10-10-associated genes across cancer lineages are MIR3121, BNIP3P4, and KRTAP4-16. Each is linked with KRTAP10-10 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP10-10-to-partner and partner-to-KRTAP10-10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP10-10→partner) and Y-score (partner→KRTAP10-10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MIR3121 →	+0.794	+5.548	<.001	.004	3	2
LUSC	BNIP3P4 →	+0.232	+5.038	<.001	.009	3	2
HNSC	KRTAP4-16 →	+0.068	+5.578	<.001	.004	3	2
SKCM	VAT1 →	+0.879	+3.504	.001	.002	3	2
UCEC	LINC02340 →	+0.354	+2.563	.003	.009	3	1
UCEC	H2AC16 →	+0.568	+3.252	.006	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 420 associations by consensus.

Exploration

KRTAP10-10 survival (RNA) · tumor vs normal (RNA) · all KRTAP10-10 data types