Across TCGA patient cohorts, KRTAP10-10 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP10-10-associated genes across cancer lineages are MEK1, N-Ras, and Annexin-1. Each is linked with KRTAP10-10 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP10-10-to-partner and partner-to-KRTAP10-10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP10-10→partner) and Y-score (partner→KRTAP10-10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.500	+3.169	.009	.019	3	1
UCEC	N-Ras →	-0.152	-2.980	.014	.036	3	1
UCEC	Annexin-1 →	+0.805	+3.321	.003	.010	3	1
UCEC	VEGFR2 →	+0.382	+2.183	.014	.035	3	1
UCEC	Caspase-7-cleavedD198 →	+0.705	+2.827	.023	.035	3	1
UCEC	ERK2 →	+0.270	+3.000	.007	.036	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

KRTAP10-10 survival (RNA) · tumor vs normal (RNA) · all KRTAP10-10 data types