Across TCGA cell cohorts, KRTAP10-1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRTAP10-1-associated genes across cancer lineages are ACER1, OR1L6, and TRARG1. Each is linked with KRTAP10-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP10-1-to-partner and partner-to-KRTAP10-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP10-1→partner) and Y-score (partner→KRTAP10-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ACER1 →	+0.081	+3.823	.009	.006	3	1
LARGE_INTESTINE	OR1L6 →	+0.022	+4.437	<.001	.004	3	1
LARGE_INTESTINE	TRARG1 →	+0.027	+3.930	<.001	.003	3	1
LARGE_INTESTINE	GRM1 →	+0.053	+3.750	<.001	.007	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

KRTAP10-1 survival (RNA) · tumor vs normal (RNA) · all KRTAP10-1 data types