KRTAP1-3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KRTAP1-3 mutation is significantly associated with the RNA expression of many other genes, with 110 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible KRTAP1-3-associated genes across cancer lineages are RDM1P1, MIR4445, and NMTRQ-TTG12-1. Each is linked with KRTAP1-3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP1-3-to-partner and partner-to-KRTAP1-3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP1-3→partner) and Y-score (partner→KRTAP1-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCRDM1P1 →+0.097+6.102<.001.00132
UCECMIR4445 →+0.360+5.671<.001<.00132
UCECNMTRQ-TTG12-1 →+0.537+3.358<.001.00632
UCECSRIP1 →+0.124+3.358.004.00632
SKCMMIR548J →+0.190+4.495<.001.00732
HNSCOR51H1 →+0.070+5.736<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 110 associations by consensus.

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