Across TCGA patient cohorts, KRTAP1-1 mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible KRTAP1-1-associated genes across cancer lineages are LINC02360, MIR4666B, and OR2L13. Each is linked with KRTAP1-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP1-1-to-partner and partner-to-KRTAP1-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP1-1→partner) and Y-score (partner→KRTAP1-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC02360 →	+0.232	+3.243	<.001	.009	3	2
SKCM	MIR4666B →	+1.011	+4.255	.007	.001	3	2
COAD	OR2L13 →	+0.116	+4.209	.002	.009	3	1
COAD	TRAJ27 →	+1.310	+4.577	<.001	.004	3	1
COAD	SRP68P1 →	+0.424	+4.266	<.001	.008	3	1
UCEC	OR2D2 →	+0.198	+4.633	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Exploration

KRTAP1-1 survival (RNA) · tumor vs normal (RNA) · all KRTAP1-1 data types