KRT8P52

Across TCGA pan-cancer cohorts, KRT8P52 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of KRT8P52’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where KRT8P52 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRT8P52 is over-expressed in tumor.

KIRP, HNSC, and COAD are the cancer types where KRT8P52 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRT8P52 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	II,III,IV	+0.408	<.001	11	view →
HNSC	Male	II,III,IV	+0.220	<.001	11	view →
COAD	Male	IV	+0.261	<.001	10	view →
KIRC	All	IV	+0.161	<.001	8	view →
LUAD	All	All	+0.140	.002	8	view →
STAD	All	II,III,IV	+0.151	<.001	7	view →
LIHC	Male	All	+0.108	<.001	7	view →
BLCA	All	All	+0.262	.001	6	view →
BRCA	All	All	+0.150	<.001	6	view →
LUSC	All	All	+0.172	<.001	5	view →
CHOL	All	All	+0.233	.001	4	view →
UCEC	All	All	+0.224	.011	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

KRT8P52–KIRP

Open the KIRP breakdown →