KRT8P23

Across TCGA pan-cancer cohorts, KRT8P23 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated KRT8P23 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher KRT8P23 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KRT8P23 expression acts as an unfavorable survival marker, although some lineages such as SKCM and CESC show a favorable association.

MESO, KIRC, and UVM are the cancer types where KRT8P23 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	II,III,IV	0.247	0.469	<.001	105	view →
KIRC	DFS	Tertile	III,IV	0.274	0.673	.003	88	view →
UVM	DFS	Tertile	All	0.326	0.913	.001	77	view →
LGG	DFS	Median	All	0.663	0.797	<.001	48	view →
LIHC	OS	Median	III,IV	0.275	0.689	<.001	45	view →
THCA	DFS	Median	IV	0.388	0.795	.002	33	view →
PAAD	OS	Quartile	All	0.404	0.722	.003	29	view →
STAD	DFS	Median	All	0.275	0.443	.007	25	view →
BRCA	DFS	Tertile	All	0.887	0.929	.012	23	view →
LUAD	DFS	Quartile	III,IV	0.517	0.778	.021	15	view →
SKCM	DFS	Tertile	All	0.689	0.545	.001	12	view →
ESCA	DFS	Quartile	II,III,IV	0.216	1.000	.020	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

KRT8P23–MESO (OS)

Open the MESO breakdown →