KRT86

Across TCGA patient cohorts, KRT86 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KRT86-associated genes across cancer lineages are MPP, CMP, and Plasma cells. Each is linked with KRT86 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRT86-to-partner and partner-to-KRT86 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPP grouped by KRT86-low versus KRT86-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT86→partner) and Y-score (partner→KRT86) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MPP →	+0.041	+3.403	<.001	.035	3	3
BRCA	CMP →	+0.041	+3.180	<.001	.032	3	2
BRCA	Plasma cells →	+0.036	+3.202	<.001	.022	3	2
LIHC	GMP →	+0.040	+3.343	.037	.016	3	2
LGG	Th2 cells →	+0.085	+4.562	.008	.005	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

MPP by KRT86 expression — COAD

Explore this box plot interactively →