KRT86

Across TCGA cell cohorts, KRT86 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,125 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRT86-associated GO terms across cancer lineages are Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway, Opsonization, and Vertebrate eye-specific patterning. Each is linked with KRT86 in more than 10 cancer types. Because this analysis shows association rather than direction, both KRT86-to-partner and partner-to-KRT86 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway grouped by KRT86-low versus KRT86-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT86→partner) and Y-score (partner→KRT86) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.127	+0.774	.001	.001	3	10
LUNG_NSCLC_LUAD	Opsonization →	+1.173	+1.296	.002	.004	3	9
UPPER_AERODIGESTIVE_TRACT	Vertebrate eye-specific patterning →	+0.772	+1.151	.001	<.001	3	9
STOMACH	Viral process →	+0.117	+1.364	<.001	<.001	3	9
SOFT_TISSUE	Negative regulation of cytokine production →	+0.056	+0.631	.005	.006	1	11
STOMACH	Viral life cycle →	+0.131	+1.386	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,125 associations by consensus.

Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway by KRT86 expression — SOFT_TISSUE

Explore this box plot interactively →