KRT85

Across TCGA patient cohorts, KRT85 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,612 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KRT85-associated GO terms across cancer lineages are Positive regulation of mitotic cell cycle, Regulation of organelle assembly, and DNA replication. Each is linked with KRT85 in more than 10 cancer types. Because this analysis shows association rather than direction, both KRT85-to-partner and partner-to-KRT85 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitotic cell cycle grouped by KRT85-low versus KRT85-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT85→partner) and Y-score (partner→KRT85) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of mitotic cell cycle →	+0.045	+0.039	<.001	<.001	3	10
STAD	Regulation of organelle assembly →	+0.043	+0.041	<.001	<.001	3	9
STAD	DNA replication →	+0.049	+0.041	<.001	<.001	3	9
STAD	Mitotic G2 DNA damage checkpoint signaling →	+0.046	+0.038	<.001	<.001	3	9
TGCT	Non-canonical Wnt signaling pathway →	+0.052	+0.071	<.001	<.001	3	9
TGCT	Regulation of establishment of planar polarity →	+0.057	+0.067	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,612 associations by consensus.

Positive regulation of mitotic cell cycle by KRT85 expression — STAD

Explore this box plot interactively →