KRT84

Across TCGA cell cohorts, KRT84 mutation is significantly associated with the RNA expression of many other genes, with 166 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRT84-associated genes across cancer lineages are OPN1MW, HMGXB4, and BLOC1S6. Each is linked with KRT84 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT84-to-partner and partner-to-KRT84 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPN1MW grouped by KRT84-low versus KRT84-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT84→partner) and Y-score (partner→KRT84) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OPN1MW →	+0.016	+4.415	.001	.007	3	1
LARGE_INTESTINE	HMGXB4 →	+0.579	+3.364	.003	.002	3	1
LARGE_INTESTINE	BLOC1S6 →	+0.457	+3.364	.005	.002	3	1
LARGE_INTESTINE	FAM149A →	+1.225	+3.364	.002	.002	3	1
LARGE_INTESTINE	B3GAT2 →	+0.209	+3.364	.001	.002	3	1
LARGE_INTESTINE	TTC33 →	+0.662	+3.169	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 166 associations by consensus.

OPN1MW by KRT84 expression — SKIN

Explore this box plot interactively →