KRT8

Across TCGA patient cohorts, KRT8 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,492 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KRT8-associated proteins across cancer lineages are KRT18, KRT8_S274, and KRT18_S42. Each is linked with KRT8 in more than 8 cancer types. Because this analysis shows association rather than direction, both KRT8-to-partner and partner-to-KRT8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KRT8 versus KRT18 in BRCA, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT8→partner) and Y-score (partner→KRT8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KRT18 →	+0.910	+1.239	<.001	<.001	3	9
BRCA	KRT8_S274 →	+1.320	+1.472	.002	<.001	3	8
BRCA	KRT18_S42 →	+0.822	+1.234	<.001	<.001	3	7
BRCA	KRT18_S60 →	+0.900	+1.199	<.001	<.001	3	7
HNSC	KRT8_S253 →	+1.318	+2.377	<.001	.001	3	7
LSCC	KRT18_S398 →	+1.688	+1.552	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,492 associations by consensus.

KRT8 vs KRT18 — BRCA

Explore this scatter interactively →