KRT78

Across TCGA pan-cancer cohorts, KRT78 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated KRT78 data layer compared with 23 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher KRT78 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated KRT78 expression acts as an unfavorable survival marker, although some lineages such as GBM and LSCC show a favorable association.

GBM, LSCC, and HNSC are the cancer types where KRT78 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Tertile	All	0.613	0.266	.002	11	view →
LSCC	DFS	Tertile	II,III,IV	1.000	0.887	.012	8	view →
HNSC	OS	Median	All	1.000	0.497	.046	4	view →
PDAC	DFS	Tertile	III,IV	0.977	0.468	.024	4	view →
CCRCC	DFS	Tertile	All	1.000	0.883	.023	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

KRT78–GBM (DFS)

Open the GBM breakdown →