KRT78

Across TCGA patient cohorts, KRT78 protein abundance is significantly associated with the RNA expression of many other genes, with 5,552 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KRT78-associated genes across cancer lineages are DSC2, LYPD3, and SCEL. Each is linked with KRT78 in more than 3 cancer types. Because this analysis shows association rather than direction, both KRT78-to-partner and partner-to-KRT78 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KRT78 versus DSC2 in LSCC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT78→partner) and Y-score (partner→KRT78) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DSC2 →	+1.315	+1.358	<.001	<.001	3	4
LSCC	LYPD3 →	+1.711	+1.296	<.001	<.001	3	3
HNSC	SCEL →	+2.308	+0.993	<.001	<.001	3	3
UCEC	ERMN →	-1.560	-0.648	<.001	.003	3	3
UCEC	EPHA2 →	+0.801	+0.754	.007	.001	3	3
LSCC	SLC10A6 →	+1.004	+0.853	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,552 associations by consensus.

KRT78 vs DSC2 — LSCC

Explore this scatter interactively →