KRT78

Across TCGA cell cohorts, KRT78 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,634 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible KRT78-associated GO terms across cancer lineages are Viral budding via host ESCRT complex, Protein targeting to ER, and Regulation of fever generation. Each is linked with KRT78 in more than 6 cancer types. Because this analysis shows association rather than direction, both KRT78-to-partner and partner-to-KRT78 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral budding via host ESCRT complex grouped by KRT78-low versus KRT78-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT78→partner) and Y-score (partner→KRT78) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Viral budding via host ESCRT complex →	+0.072	+0.197	.001	.002	3	7
LARGE_INTESTINE	Protein targeting to ER →	+0.052	+0.125	.001	.006	3	7
BREAST	Regulation of fever generation →	+1.072	+0.404	<.001	.003	3	7
URINARY_TRACT	Neuromuscular process controlling balance →	-0.221	-0.632	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Positive regulation of dopamine uptake involved in synaptic transmission →	-0.164	-0.566	<.001	.004	3	6
URINARY_TRACT	NMDA selective glutamate receptor signaling pathway →	+0.273	+0.425	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,634 associations by consensus.

Viral budding via host ESCRT complex by KRT78 expression — LARGE_INTESTINE

Explore this box plot interactively →