Across TCGA patient cohorts, KRT76 protein abundance is significantly associated with the RNA expression of many other genes, with 1,987 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KRT76-associated genes across cancer lineages are COL7A1, SLC2A1, and CHST3. Each is linked with KRT76 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT76-to-partner and partner-to-KRT76 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT76→partner) and Y-score (partner→KRT76) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	COL7A1 →	+1.627	+0.902	<.001	<.001	3	2
LSCC	SLC2A1 →	+1.406	+1.137	.001	.004	3	2
LSCC	CHST3 →	+0.664	+0.912	.001	.001	3	2
LSCC	KRT17 →	+2.240	+1.174	.008	.006	3	2
LSCC	KRT82 →	+0.091	+1.138	.001	.002	3	2
LSCC	PGLYRP4 →	+1.355	+1.172	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,987 associations by consensus.

Exploration

KRT76 survival (RNA) · tumor vs normal (RNA) · all KRT76 data types