Across TCGA cell cohorts, KRT76 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible KRT76-associated genes across cancer lineages are CCDC140, PRR23A, and RBMY1F. Each is linked with KRT76 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT76-to-partner and partner-to-KRT76 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT76→partner) and Y-score (partner→KRT76) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	CCDC140 →	+0.094	+4.035	.002	.003	3	1
PANCREAS	PRR23A →	+0.049	+3.700	.005	.008	3	1
SKIN	RBMY1F →	+0.052	+4.437	<.001	.004	3	1
SKIN	OR5P2 →	+0.025	+3.684	.008	.006	3	1
SKIN	KRTAP6-1 →	+0.060	+4.437	<.001	.004	3	1
SKIN	MBD3L5 →	+0.026	+5.000	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

KRT76 survival (RNA) · tumor vs normal (RNA) · all KRT76 data types