KRT74

Across TCGA patient cohorts, KRT74 protein abundance is significantly associated with the RNA expression of many other genes, with 724 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible KRT74-associated genes across cancer lineages are CHPT1, LINC02772, and CRY2. Each is linked with KRT74 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT74-to-partner and partner-to-KRT74 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KRT74 versus CHPT1 in LUAD, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT74→partner) and Y-score (partner→KRT74) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CHPT1 →	+1.174	+1.737	.003	.003	3	2
LUAD	LINC02772 →	+0.858	+1.428	.002	.004	3	2
HNSC	CRY2 →	-0.596	-0.890	.009	.006	3	1
HNSC	RAB1A →	-0.346	-1.002	.004	.002	3	1
HNSC	HRCT1 →	-0.533	-0.747	<.001	.004	3	1
HNSC	AP2A1 →	-0.329	-0.710	.008	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 724 associations by consensus.

KRT74 vs CHPT1 — LUAD

Explore this scatter interactively →