Across TCGA patient cohorts, KRT73 mutation is significantly associated with the RNA expression of many other genes, with 2,086 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT73-associated genes across cancer lineages are THUMPD1P1, RNA5SP21, and PNPLA3. Each is linked with KRT73 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRT73-to-partner and partner-to-KRT73 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT73→partner) and Y-score (partner→KRT73) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	THUMPD1P1 →	+0.048	+4.742	.003	.003	3	3
LGG	RNA5SP21 →	+0.629	+4.296	<.001	.008	3	3
SKCM	PNPLA3 →	+0.824	+2.341	.001	.003	3	3
LUSC	RNU6-1094P →	+0.110	+5.014	<.001	.001	3	3
LIHC	RN7SL149P →	+0.174	+5.447	<.001	.005	3	2
LIHC	HSPD1P18 →	+0.205	+5.647	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,086 associations by consensus.

Exploration

KRT73 survival (RNA) · tumor vs normal (RNA) · all KRT73 data types