KRT7

Across TCGA patient cohorts, KRT7 mutation is significantly associated with the RNA expression of many other genes, with 1,796 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT7-associated genes across cancer lineages are RPL31P47, PDS5A, and VAPA. Each is linked with KRT7 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRT7-to-partner and partner-to-KRT7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL31P47 grouped by KRT7-low versus KRT7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT7→partner) and Y-score (partner→KRT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL31P47 →	+0.302	+2.384	<.001	.006	3	3
UCEC	PDS5A →	+0.618	+3.839	.002	<.001	3	3
SKCM	VAPA →	+0.358	+2.280	.007	.005	3	3
COAD	OR13D3P →	+0.089	+3.541	.005	.001	3	3
GBM	NF1P2 →	+0.028	+5.584	<.001	.003	3	2
GBM	MIR7854 →	+0.712	+4.969	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,796 associations by consensus.

RPL31P47 by KRT7 expression — UCEC

Explore this box plot interactively →