KRT6C

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KRT6C protein abundance is significantly associated with the RNA expression of many other genes, with 8,139 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KRT6C-associated genes across cancer lineages are SLC5A1, KCNK10, and CA2. Each is linked with KRT6C in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT6C-to-partner and partner-to-KRT6C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KRT6C versus SLC5A1 in HNSC, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT6C→partner) and Y-score (partner→KRT6C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCSLC5A1 →+0.829+0.852.001.00232
HNSCKCNK10 →+0.936+1.029<.001<.00132
HNSCCA2 →+1.505+1.377<.001<.00132
LSCCNDRG1 →+1.197+1.101<.001<.00132
HNSCPLIN3 →+0.764+0.982.001<.00132
LSCCCNFN →+1.445+1.190.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,139 associations by consensus.

KRT6C vs SLC5A1 — HNSC

Per-sample scatter of KRT6C vs SLC5A1 in HNSC (Pearson r = 0.27).

Explore this scatter interactively →

Exploration