Across TCGA patient cohorts, KRT6B RNA expression is significantly associated with the protein abundance of many other proteins, with 12,665 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KRT6B-associated proteins across cancer lineages are KRT16, KRT17, and KRT6A. Each is linked with KRT6B in more than 5 cancer types. Because this analysis shows association rather than direction, both KRT6B-to-partner and partner-to-KRT6B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT6B→partner) and Y-score (partner→KRT6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KRT16 →	+1.800	+4.038	<.001	<.001	3	6
UCEC	KRT17 →	+1.254	+1.159	<.001	.002	3	6
UCEC	KRT6A →	+2.122	+1.794	<.001	<.001	3	6
LSCC	TRIM29_S21 →	+1.013	+2.199	<.001	<.001	3	6
LSCC	SERPINB3 →	+1.642	+2.676	<.001	<.001	3	5
LUAD	SERPINB5 →	+1.684	+1.018	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,665 associations by consensus.

Exploration

KRT6B survival (RNA) · tumor vs normal (RNA) · all KRT6B data types