Across TCGA patient cohorts, KRT6B protein abundance is significantly associated with the RNA expression of many other genes, with 11,336 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KRT6B-associated genes across cancer lineages are KRT6A, PI3, and S100A7. Each is linked with KRT6B in more than 6 cancer types. Because this analysis shows association rather than direction, both KRT6B-to-partner and partner-to-KRT6B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT6B→partner) and Y-score (partner→KRT6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KRT6A →	+3.316	+2.170	<.001	<.001	3	7
UCEC	PI3 →	+2.984	+2.230	<.001	<.001	3	5
UCEC	S100A7 →	+3.008	+2.134	<.001	<.001	3	5
LSCC	CLCA2 →	+2.276	+1.759	<.001	<.001	3	4
LSCC	KRT17 →	+2.062	+1.389	<.001	<.001	3	4
BRCA	GRHL1 →	+0.806	+1.260	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,336 associations by consensus.

Exploration

KRT6B survival (RNA) · tumor vs normal (RNA) · all KRT6B data types