Across TCGA patient cohorts, KRT6A RNA expression is significantly associated with the protein abundance of many other proteins, with 13,138 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KRT6A-associated proteins across cancer lineages are KRT17, SERPINB5, and S100A2. Each is linked with KRT6A in more than 7 cancer types. Because this analysis shows association rather than direction, both KRT6A-to-partner and partner-to-KRT6A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT6A→partner) and Y-score (partner→KRT6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KRT17 →	+1.826	+2.040	<.001	<.001	3	8
LUAD	SERPINB5 →	+1.534	+2.217	<.001	<.001	3	7
PDAC	S100A2 →	+2.266	+2.688	<.001	<.001	3	7
HNSC	AHNAK2 →	+0.895	+1.469	<.001	<.001	3	7
HNSC	AHNAK2_S3408 →	+1.285	+1.431	<.001	<.001	3	7
LSCC	KRT16 →	+1.667	+3.275	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,138 associations by consensus.

Exploration

KRT6A survival (RNA) · tumor vs normal (RNA) · all KRT6A data types