Across TCGA patient cohorts, KRT6A protein abundance is significantly associated with the RNA expression of many other genes, with 11,446 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KRT6A-associated genes across cancer lineages are KRT16, TRIM29, and ADGRF4. Each is linked with KRT6A in more than 7 cancer types. Because this analysis shows association rather than direction, both KRT6A-to-partner and partner-to-KRT6A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT6A→partner) and Y-score (partner→KRT6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KRT16 →	+3.050	+1.546	<.001	<.001	3	8
BRCA	TRIM29 →	+1.826	+2.106	<.001	<.001	3	6
LSCC	ADGRF4 →	+1.481	+1.626	<.001	<.001	3	6
LSCC	KRT14 →	+3.453	+1.455	<.001	<.001	3	6
UCEC	GJB2 →	+1.927	+1.749	<.001	<.001	3	6
HNSC	KRT6C →	+2.580	+0.925	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,446 associations by consensus.

Exploration

KRT6A survival (RNA) · tumor vs normal (RNA) · all KRT6A data types