Across TCGA patient cohorts, KRT42P mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT42P-associated genes across cancer lineages are RNA5-8SN2, MIR6133, and DEFB104A. Each is linked with KRT42P in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT42P-to-partner and partner-to-KRT42P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT42P→partner) and Y-score (partner→KRT42P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNA5-8SN2 →	+0.219	+7.816	<.001	.008	3	1
UCEC	MIR6133 →	+0.539	+4.567	.002	.001	3	1
UCEC	DEFB104A →	+0.150	+6.151	<.001	<.001	3	1
SKCM	RNA5-8SN3 →	+0.218	+7.816	<.001	.008	3	1
SKCM	RNU6-709P →	+0.483	+7.816	<.001	.008	3	1
UCEC	MIR449A →	+0.459	+4.997	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

KRT42P survival (RNA) · tumor vs normal (RNA) · all KRT42P data types