Across TCGA cell cohorts, KRT39 RNA expression is significantly associated with the go_rna of many other GO terms, with 564 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible KRT39-associated GO terms across cancer lineages are Negative regulation of regulatory T cell differentiation, Regulation of tumor necrosis factor superfamily cytokine production, and CD8-positive, alpha-beta T cell activation. Each is linked with KRT39 in more than 6 cancer types. Because this analysis shows association rather than direction, both KRT39-to-partner and partner-to-KRT39 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT39→partner) and Y-score (partner→KRT39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of regulatory T cell differentiation →	+0.148	+0.193	<.001	.001	3	7
CNS	Regulation of tumor necrosis factor superfamily cytokine production →	+0.037	+0.061	.005	.008	3	7
UPPER_AERODIGESTIVE_TRACT	CD8-positive, alpha-beta T cell activation →	+0.097	+0.207	<.001	<.001	3	6
CNS	Antigen processing and presentation of peptide antigen via MHC class I →	+0.152	+0.085	<.001	<.001	3	6
SOFT_TISSUE	Cytoplasmic pattern recognition receptor signaling pathway →	+0.053	+0.081	.001	.008	3	6
BREAST	Cytosol to endoplasmic reticulum transport →	+0.209	+0.114	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 564 associations by consensus.

Exploration

KRT39 survival (RNA) · tumor vs normal (RNA) · all KRT39 data types