Across TCGA cell cohorts, KRT39 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KRT39-associated genes across cancer lineages are IL1F10, GALP, and INSL5. Each is linked with KRT39 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT39-to-partner and partner-to-KRT39 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT39→partner) and Y-score (partner→KRT39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	IL1F10 →	+0.299	+5.369	<.001	.004	3	1
SOFT_TISSUE	GALP →	+0.055	+4.930	<.001	.008	3	1
LARGE_INTESTINE	INSL5 →	+0.385	+3.626	<.001	.006	3	1
LARGE_INTESTINE	FMR1NB →	+0.238	+3.716	<.001	.008	3	1
LARGE_INTESTINE	TFDP3 →	+0.031	+3.196	<.001	.007	3	1
LARGE_INTESTINE	CENPVL1 →	+0.150	+3.510	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Exploration

KRT39 survival (RNA) · tumor vs normal (RNA) · all KRT39 data types