Across TCGA cell cohorts, KRT39 mutation is significantly associated with the mutation status of many other genes, with 3,243 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRT39-associated genes across cancer lineages are ITGB6, GGCX, and EFR3A. Each is linked with KRT39 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRT39-to-partner and partner-to-KRT39 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT39→partner) and Y-score (partner→KRT39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ITGB6 →	+4.584	+4.584	<.001	<.001	1	3
LARGE_INTESTINE	GGCX →	+4.000	+3.459	<.001	<.001	1	3
LARGE_INTESTINE	EFR3A →	+2.125	+3.278	.001	.001	1	3
SKIN	C5AR1 →	+4.392	+4.392	.009	.009	1	2
LARGE_INTESTINE	OGFOD1 →	+3.415	+3.215	.002	.002	1	2
LARGE_INTESTINE	PPP1R13B →	+2.152	+2.787	.005	.005	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,243 associations by consensus.

Exploration

KRT39 survival (RNA) · tumor vs normal (RNA) · all KRT39 data types