KRT37

Across TCGA patient cohorts, KRT37 mutation is significantly associated with the RNA expression of many other genes, with 4,611 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT37-associated genes across cancer lineages are DHRS11, SNW1, and MDC1. Each is linked with KRT37 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRT37-to-partner and partner-to-KRT37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DHRS11 grouped by KRT37-low versus KRT37-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT37→partner) and Y-score (partner→KRT37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DHRS11 →	+0.505	+1.958	<.001	.002	3	3
UCEC	SNW1 →	+0.393	+1.928	.001	<.001	3	3
UCEC	MDC1 →	+0.463	+2.130	<.001	.002	3	3
SKCM	RAD17 →	+0.446	+3.373	.007	.004	3	3
SKCM	PCGF6 →	+0.549	+2.449	<.001	<.001	3	3
SKCM	PEX13 →	+0.372	+1.733	.006	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,611 associations by consensus.

DHRS11 by KRT37 expression — UCEC

Explore this box plot interactively →