KRT37

Across TCGA pan-cancer cohorts, KRT37 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated KRT37 data layer compared with 9 for mutation status.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher KRT37 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KRT37 expression acts as an unfavorable survival marker, although some lineages such as BRCA and ESCA show a favorable association.

SKCM, BRCA, and PCPG are the cancer types where KRT37 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	All	0.778	0.886	.003	36	view →
BRCA	DFS	Tertile	III,IV	0.938	0.813	.003	27	view →
PCPG	DFS	Tertile	All	0.602	0.873	.007	27	view →
ESCA	OS	Tertile	II,III,IV	0.684	0.417	.012	26	view →
COAD	OS	Median	II,III,IV	0.434	0.661	.001	22	view →
STAD	DFS	Tertile	III,IV	0.600	0.284	.036	10	view →
SARC	OS	Tertile	All	0.744	0.838	.013	9	view →
LIHC	OS	Tertile	All	0.184	0.518	.049	9	view →
ACC	DFS	Tertile	II,III,IV	0.419	0.747	.034	9	view →
CHOL	DFS	Tertile	II,III,IV	1.000	0.147	.041	9	view →
KIRP	DFS	Tertile	II,III,IV	0.453	0.873	.010	8	view →
THYM	DFS	Median	II,III,IV	0.762	0.958	.026	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

KRT37–SKCM (OS)

Open the SKCM breakdown →