KRT37

Across TCGA cell cohorts, KRT37 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRT37-associated genes across cancer lineages are FOXB2, H2BC1, and H2AC1. Each is linked with KRT37 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT37-to-partner and partner-to-KRT37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOXB2 grouped by KRT37-low versus KRT37-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT37→partner) and Y-score (partner→KRT37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	FOXB2 →	+1.663	+6.266	<.001	<.001	3	2
SOFT_TISSUE	H2BC1 →	+0.325	+4.977	<.001	.002	3	1
SOFT_TISSUE	H2AC1 →	+0.145	+4.977	<.001	.002	3	1
OESOPHAGUS	CENPVL1 →	+0.246	+4.906	<.001	.006	3	1
LUNG_NSCLC_LUAD	NXNL1 →	+0.052	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	POM121L12 →	+0.030	+6.266	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

FOXB2 by KRT37 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →