KRT37

Across TCGA cell cohorts, KRT37 mutation is significantly associated with the mutation status of many other genes, with 1,745 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRT37-associated genes across cancer lineages are CNTN4, GUCY2C, and ROBO4. Each is linked with KRT37 in more than 4 cancer types. Because this analysis shows association rather than direction, both KRT37-to-partner and partner-to-KRT37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CNTN4 grouped by KRT37-low versus KRT37-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT37→partner) and Y-score (partner→KRT37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CNTN4 →	+4.187	+5.000	.008	.008	1	5
BLOOD_Leukemia	GUCY2C →	+4.145	+4.635	.001	.001	1	4
LUNG_SCLC	ROBO4 →	+2.843	+4.193	.007	.007	1	4
BLOOD_Lymphoma	SEC24A →	+3.510	+4.108	.003	.003	1	3
LUNG_NSCLC_LUAD	SPECC1 →	+5.772	+5.772	.002	.002	1	3
BLOOD_Lymphoma	RFX5 →	+5.247	+4.429	.005	.005	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,745 associations by consensus.

CNTN4 by KRT37 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →