KRT34

Across TCGA cell cohorts, KRT34 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,184 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KRT34-associated GO terms across cancer lineages are Blood coagulation, extrinsic pathway, Blood coagulation, intrinsic pathway, and Dentinogenesis. Each is linked with KRT34 in more than 11 cancer types. Because this analysis shows association rather than direction, both KRT34-to-partner and partner-to-KRT34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Blood coagulation, extrinsic pathway grouped by KRT34-low versus KRT34-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT34→partner) and Y-score (partner→KRT34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Blood coagulation, extrinsic pathway →	+1.231	+1.932	<.001	<.001	3	12
LARGE_INTESTINE	Blood coagulation, intrinsic pathway →	+0.227	+0.852	<.001	.006	3	12
BONE	Dentinogenesis →	+2.323	+1.811	<.001	.001	3	12
SOFT_TISSUE	Protein lipidation →	+0.087	+1.268	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Protein activation cascade →	+0.415	+2.472	.001	.006	3	11
BONE	Negative regulation of plasminogen activation →	+1.295	+1.797	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,184 associations by consensus.

Blood coagulation, extrinsic pathway by KRT34 expression — SOFT_TISSUE

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