KRT34

Across TCGA pan-cancer cohorts, KRT34 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated KRT34 data layer compared with 8 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher KRT34 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRT34 expression acts as an unfavorable survival marker, although some lineages such as SKCM and UCS show a favorable association.

KIRC, MESO, and COAD are the cancer types where KRT34 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.527	0.704	<.001	106	view →
MESO	OS	Tertile	All	0.381	0.643	<.001	68	view →
COAD	OS	Quartile	III,IV	0.537	0.839	<.001	61	view →
LIHC	OS	Tertile	All	0.622	0.813	<.001	60	view →
KIRP	OS	Quartile	All	0.581	0.858	.005	52	view →
PAAD	DFS	Median	All	0.223	0.501	.001	47	view →
STAD	OS	Quartile	II,III,IV	0.281	0.634	.003	36	view →
GBM	DFS	Tertile	All	0.173	0.290	<.001	36	view →
SCLC	DFS	Tertile	II,III,IV	0.219	0.868	<.001	27	view →
UVM	OS	Tertile	All	0.220	0.917	<.001	27	view →
SKCM	DFS	Tertile	II,III,IV	0.332	0.204	.009	20	view →
SARC	OS	Quartile	All	0.736	0.855	.008	20	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

KRT34–KIRC (DFS)

Open the KIRC breakdown →