KRT33A

Across TCGA cell cohorts, KRT33A mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible KRT33A-associated genes across cancer lineages are UGT2B28, CCL1, and FAM181A. Each is linked with KRT33A in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT33A-to-partner and partner-to-KRT33A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UGT2B28 grouped by KRT33A-low versus KRT33A-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT33A→partner) and Y-score (partner→KRT33A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	UGT2B28 →	+0.236	+5.369	<.001	.004	3	1
LUNG_NSCLC_LUAD	CCL1 →	+0.057	+5.189	<.001	<.001	3	1
LUNG_NSCLC_LUAD	FAM181A →	+0.067	+5.266	<.001	.001	3	1
LUNG_NSCLC_LUAD	OR8B12 →	+0.052	+4.734	<.001	.002	3	1
LUNG_NSCLC_LUAD	CCT8L2 →	+0.032	+4.371	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR8D2 →	+0.059	+4.371	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

UGT2B28 by KRT33A expression — SOFT_TISSUE

Explore this box plot interactively →