KRT32

Across TCGA cell cohorts, KRT32 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible KRT32-associated genes across cancer lineages are PNLIPRP1, GHRH, and OR2T1. Each is linked with KRT32 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT32-to-partner and partner-to-KRT32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PNLIPRP1 grouped by KRT32-low versus KRT32-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT32→partner) and Y-score (partner→KRT32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PNLIPRP1 →	+0.033	+4.947	<.001	.001	3	1
SKIN	GHRH →	+0.402	+3.103	.002	.004	3	1
SKIN	OR2T1 →	+0.005	+3.700	<.001	.009	3	1
SKIN	TGIF2LY →	+0.129	+2.925	.008	.007	3	1
SKIN	C7orf77 →	+0.075	+4.000	<.001	<.001	3	1
LARGE_INTESTINE	TSKS →	+0.217	+3.807	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

PNLIPRP1 by KRT32 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →