KRT32

Across TCGA pan-cancer cohorts, KRT32 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated KRT32 data layer compared with 6 for mutation status.

The strongest signal is observed in small cell lung cancer (SCLC), where higher KRT32 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KRT32 expression acts as an unfavorable survival marker, although some lineages such as BRCA and ESCA show a favorable association.

SCLC, KIRC, and LGG are the cancer types where KRT32 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Quartile	II,III,IV	0.373	0.733	<.001	42	view →
KIRC	OS	Tertile	All	0.522	0.710	.002	36	view →
LGG	OS	Tertile	All	0.374	0.474	.015	31	view →
BRCA	OS	Quartile	III,IV	0.916	0.758	.006	27	view →
ESCA	OS	Median	All	1.000	0.670	.026	25	view →
GBM	DFS	Tertile	All	0.108	0.358	<.001	21	view →
UVM	OS	Tertile	III,IV	0.178	0.933	<.001	15	view →
UCS	DFS	Quartile	All	0.635	0.335	.022	14	view →
PRAD	OS	Median	All	1.000	0.817	.005	12	view →
LUAD	DFS	Tertile	III,IV	0.604	0.388	.017	10	view →
CHOL	OS	Tertile	II,III,IV	0.381	0.893	.006	9	view →
SARC	OS	Quartile	All	0.360	0.573	.007	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

KRT32–SCLC (OS)

Open the SCLC breakdown →