Across TCGA patient cohorts, KRT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,039 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible KRT3-associated GO terms across cancer lineages are Negative regulation of release of cytochrome c from mitochondria, Autocrine signaling, and Desmosome organization. Each is linked with KRT3 in more than 12 cancer types. Because this analysis shows association rather than direction, both KRT3-to-partner and partner-to-KRT3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT3→partner) and Y-score (partner→KRT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of release of cytochrome c from mitochondria →	+0.063	+0.151	<.001	<.001	3	13
ESCA	Autocrine signaling →	+0.135	+0.883	<.001	<.001	3	13
TGCT	Desmosome organization →	+0.084	+0.163	<.001	<.001	3	12
ESCA	Skin epidermis development →	+0.053	+0.712	<.001	<.001	3	11
STAD	Regulation of Notch signaling pathway →	+0.052	+0.127	<.001	<.001	3	11
UCS	Mammary gland epithelial cell proliferation →	+0.056	+0.338	<.001	.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,039 associations by consensus.

Exploration

KRT3 survival (RNA) · tumor vs normal (RNA) · all KRT3 data types