Across TCGA patient cohorts, KRT3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,871 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KRT3-associated genes across cancer lineages are SULT2B1, NDRG1, and SLC2A1. Each is linked with KRT3 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRT3-to-partner and partner-to-KRT3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT3→partner) and Y-score (partner→KRT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SULT2B1 →	+1.843	+1.031	.002	.006	3	3
LSCC	NDRG1 →	+1.652	+1.180	<.001	<.001	3	2
LSCC	SLC2A1 →	+1.509	+1.053	<.001	<.001	3	2
HNSC	TP53AIP1 →	+0.925	+0.738	<.001	<.001	3	2
LSCC	GJB6 →	+3.346	+1.327	<.001	<.001	3	2
HNSC	LYPD3 →	+1.143	+0.664	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,871 associations by consensus.

Exploration

KRT3 survival (RNA) · tumor vs normal (RNA) · all KRT3 data types